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As proof-of-principle that manipulation of Section I metabolism would alter the in vivo effects of the SCBs, hypothermic outcomes of 3 mg/kg JWH-018 or 5F-AB-PINACA were being decided making use of radiotelemetry within the presence or absence of the worldwide CYP450 inhibitor one-ABT in mice (JWH-018 generates effects in animals similar to Those p